MASSACHUSETTS INSTITUTE OF TECHNOLOGY | RAGON INSTITUTE
We investigate crosstalk between CD8+ T cells and their environment at a molecular level, by dissecting the biological and metabolic programs engaged under conditions of stress. Using an array of approaches to model and perturb the local microenvironment, our research aims to reveal both the adaptive molecular changes as well as intrinsic vulnerabilities in T cells that arise within the tumor niche. Our goal is to understand how disease states remodel the fundamental mechanisms that regulate immune cell function and contribute to pathogenesis.
Molecular adaptations in immune cells enabling function under stress
Ringel Lab Mission
We strive to make the world a better place by answering essential questions at the intersection between immunology and cancer biology.
We believe that our discoveries will lead to fundamental new insights on how the immune system adapts to stress to improve human health and combat disease.
We commit to the core principles of rigor in science, objective evaluation, ethical conduct, collaboration, and honesty.
We foster an inclusive, constructive, and respectful training environment to educate the next generation of scientists and thinkers.
